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Sydney Cord Blood Bank

 Kids with Cancer Foundation's enormously generous donation of $500,000 in 2003 to Australia's first stem cell facility, the "Sydney Cord Blood Bank", greatly assisted with the capital funding needed to open this facility, without your donation there would be no Stem Cell Facility (Sydney Cord Blood Bank).

Thanks to that support the Sydney Children’s Hospital, Randwick has established Australia’s first Stem Cell facility dedicated to the treatment of children’s diseases. Through the innovative use of non-embryonic stem cells, the Hospital will lead the world in the treatment of children’s cancer. Your contribution has enabled us to build this new facility.  We are extremely grateful for the opportunity you have allowed CCC&BD to pave the way forward in this innovative treatment (Sydney Children's Hospital).

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Over 850 stem cell transplants were performed at Sydney Children's Hospital (to 2012) making it the oldest and largest paediatric program in Australasia. The program has nationally lead the way having performed the first cord transplant, first double cord transplant and boasts the longest surviving transplant recipient in the Southern Hemisphere. 

Stem transplant is often the only curative option for paediatric patients with high risk or relapsed cancers and for many non-malignant diseases including immunedeficiency disorders, marrow failure, metabolic diseases and thalassemia. 

Our research team has a broad portfolio aimed at improving successful outcomes through preclinical and clinical initiatives.  Specific barriers including engraftment, infection, graft versus host disease, supportive care, relapse, quality standards and medication safety are key areas ofongoing research. 


 Recently as part of our 2017, $446,000 donation to the Kids Cancer Centre (KCC) at Sydney Children’s Hospital, Kids with Cancer Foundation agreed to fund a new position in the KCC, ‘The Kids with Cancer Foundation Bone Marrow Transplant Fellow’. Dr. Vasant Chinnabhandar is the new BMT Fellow. 

In the first year of the fellowship alone, the new Bone-Marrow Transplant Fellow will teach up to 80 medical staff and have over 75,000 touch points of contact with patients. Training the next generation of specialist paediatric haematologist and oncologists and researchers is essential to the provision of future cancer care for children in Australia.

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Dr. Vasant Chinnabhandar is the
Kids with Cancer Foundation BMT Fellow. 

Kids with Cancer Foundation's enormously generous donation of $500,000 in 2003 to Australia's first stem cell facility, the "Sydney Cord Blood Bank", greatly assisted with the capital funding needed to open this facility. Through the innovative use of non-embryonic stem cells, the Hospital will lead the world in the treatment of children's cancer. Your signification contribution will assist the Hospital conduct crucial research in this area which we hope will mean less time in Hospital for transplant patients, less infection, lower cost and most importantly, improved survival rates for these brave children.

Every year 350 children in NSW are diagnosed with some form of cancer or blood disorder. Bone Marrow and Stem Cell transplants now play a major role in the treatment of cancer and other blood disorders, in particular leukaemia. Produced within the bone marrow, stem cells are valuable in fighting diseases, because of their ability to regenerate the immune system.

Only fifty percent of patients find compatible bone marrow donors from their immediate or extended family or in bone marrow donor registries. The remaining fifty percent of patients must find a suitable unrelated donor in Cord Blood Banks.

One of the greatest risks for any transplant patient is the treatment required prior to the transplant when the patient’s marrow stops producing white cells, red cells and platelets. This period places the patient at life threatening risks of anaemia, haemorrhages and infections. Children who have a bone marrow transplant need multiple blood transfusions, antibiotic therapy and will suffer from painful mouth ulcers during the more than two week period it takes for the new marrow to regrow after the transplant.

Innovations:

The Australian Stem Cell Facility will provide the following groundbreaking initiatives:

  • Ability to grow, multiply and expand the number of stem cells available for transplant for children in life threatening situations caused by cancer and other blood disorders.
  • By culturing the cells for up to one week prior to the transplant we will increase the cell number and diversity, so that transfusion, infection and mouth ulceration are avoided.
  • Significantly reduce the time taken for the new marrow to reach normal functioning in the child having the transplant.
  • Greatly reduce the number of patients who die while waiting for a transplant.
  • Possibility of transplants being performed on an "Outpatient" basis diminishing the need for children to remain isolated in one room for up to two months.

All this means less time in hospital, less infection, less supportive treatment, lower cost and most importantly, improved survival rates for these brave children

Our research team has a broad portfolio aimed at improving successful outcomes through preclinical and clinical initiatives.  Specific barriers including engraftment, infection, graft versus host disease, supportive care, relapse, quality standards and medication safety are key areas ofongoing research.

Further we have active funded research in law and ethics of decision making around stem cell transplantation and cord blood and educational initiatives to improve understanding for parents, patients and education staff. Professor Glenn Marshall AM

 


We urge you to consider the children in a hospital near you.  Please donate, post cheques to: Kids with Cancer Foundation, PO Box 135 Westmead NSW 2145 or for credit cards: free-call any donations to 1800 255522, and we guarantee that 100% of these donations will be passed to families, or use this Donate now button or at the top of the page.

 

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